Marie: the first complete human printed in 3D to help in radiotherapies


CATEGORY: Medical advances BRAND: Universidad de Luisiana

The phantom Project, also known as Marie, will facilitate tests and radiation exposures on a life-size humanoid to find the best angle for dose distribution.



Meagan Moore, a bioengineer at the University of Louisiana, has been working to 3D print the first life-size "human body" for radiotherapy research. Moore justified the name of his project and the reason for it: "Phantoms have been used in medical and health physics for decades as substitutes for human tissue, the problem is that most dosimetric models are currently performed from a standard when people who get cancer are from different types of bodies and therefore there are no personalized phantoms. "


Today's phantoms tend to have high costs, around $ 40,000, do not have limbs and do not represent all body types, Marie (as the first printed humanoid is known) represents a more realistic human body and its printing costs only about $ 500 . With the use of 3D images of five real women who were acquired at the Pennington Biomedical Research Center, Moore developed a realistic female phantom made of bioplastic that can be filled with water to establish a variable density similar to a patient: "Specifically I wanted to work with a woman because, in science, women are generally not studied because they are considered complex due to a variety of reasons, "says Moore. "I want a person with the most complex geometry."


Marie needed 136 hours to be printed in four sections, with the BigRep printer. To connect the sections, Moore used a combination of welding, friction welding, and sandblasting. He even used a hammer and a chisel to remove pieces of plastic without harming Marie. The main problem was finding out where to place the tubing to measure the dose. He ended up going down the middle line from his head to his pelvic floor.


In October, Moore took Marie to the facilities of the UW Medical Center in Seattle, where researchers were interested in trying fast neutron therapy with her. This type of therapy, a specialized and powerful form of external-beam radiation therapy, is often used to treat certain tumors that are resistant to radiation, which means they are extremely difficult to eliminate with X-ray radiation therapy.


Marie, whose name is a combination of Marie Curie (radiation researcher), Marie Antoinette (removable head) and Marie Laveau (purple symbolism), Moore hopes that personalized replicas of her will be created and used in the medical field to, in a way More precise treatment of patients with cancer: "What I would like to see in this project is the research that will be used as a fundamental work to personalize cancer treatments for people with more complex treatments." Children and patients with breast cancer have A really different morphology that is usually very difficult to treat, I find that the more we learn about any body, the more complex it will be, we are still making mistakes with medicine on many levels.


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